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In a current analyze, we noted the identification and the characterization of a completely new atypical opioid receptor with distinctive negative regulatory Attributes to opioid peptides.1 Our final results showed that ACKR3/CXCR7, hitherto generally known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, can also be a wide-spectr